How can I tell if my TWAIN compliant scanner works natively on an Intel based mac?

Navigate in the Finder to /Library/Image Capture/TWAIN Data Sources and look for your driver. Choose Get Info on the bundle and you will see something like the first picture below. If it says PowerPC next to the Kind like it does below, then the driver is not Intel native and you must run ReceiptWallet or DocumentWallet under Rosetta. If it says Universal, then you can run ReceiptWallet or DocumentWallet normally. If Get Info indicates that it is a folder, you'll need to navigate further down into the folder into Contents/MacOS and then click on your scanner driver and then choose Get Info. You will see something like the second picture below. It it says PowerPC, then you have to run ReceiptWallet or DocumentWallet under Rosetta.